Serving Detroit and Metro Detroit. Licensed providers. US pharmacies. Discreet shipping.
Perimenopause Care by Golden Glow, product image is illustrative

Product image is illustrative. Your medication and packaging may look different.

No. 15 · Hormones

Perimenopause Care

Symptoms, answers, options

Prescription

Perimenopause is the transition before menopause, when hormones swing and periods change, and it most often begins between ages 45 and 55. Symptoms like night sweats, sleep trouble, mood changes, weight changes and brain fog are common, and a licensed provider can review them in an online visit and discuss hormone and non-hormone options.

For the transition before menopause.

OptionMonthlyQuarterly, 3 monthsStart
Estradiol tablets$120$155about $52 a monthStart
Progesterone capsules$140$210about $70 a monthStart
Estradiol patch$195$375about $125 a monthStart

Prices include the online visit, licensed provider review, medication and shipping. Quarterly plans ship three months at a time. Cancel or pause anytime. Available online in Detroit, Metro Detroit and across Michigan, and in other states where our providers are licensed.

Online visits for Detroit, Metro Detroit and Michigan. Questions first? Email support@hoolongevity.com or call (586) 321-3377.

Who it's for

  • Women in their late 30s, 40s or early 50s with new cycle changes or symptoms
  • Women who still have periods but feel different
  • Women who were told to wait it out and want options

Not for

  • Emergencies: call 911 for chest pain or stroke symptoms
  • Anyone who needs an in-person exam first, which your provider will advise

Your licensed provider reviews your full history and decides what is appropriate.

How it works

01

Track your cycle and symptoms (our symptom checklist helps)

02

Complete the online visit

03

A licensed provider reviews your history and discusses options, including hormone therapy if appropriate

04

Medication ships from a licensed US pharmacy

What's included

  • Online visit and licensed provider review
  • Medication if prescribed, at the prices on the menopause page
  • Shipping in discreet packaging
  • Follow-up messaging

Important safety information

  • Standard hormone therapy doses are not birth control, so some women in perimenopause still need contraception.
  • Other conditions, such as thyroid problems, can cause similar symptoms, so your provider may suggest checking for them.
  • If you have significant anxiety, panic or low mood, tell your provider. If you ever have thoughts of harming yourself, call or text 988.

Prescription only. A licensed provider reviews your health history in an online visit and decides whether this program is appropriate for you. Tell your provider about every medication, supplement, allergy and condition, and whether you are pregnant, trying to conceive or breastfeeding. If you have a severe reaction, trouble breathing, chest pain or swelling of the face or throat, call 911.

Full details: safety information. Updated November 3, 2026.

Questions, answered

Straight answers about Perimenopause Care.

What are the signs of perimenopause in your 40s, even if your periods are still regular?

Perimenopause can start while you still have periods, and common signs include cycle changes, hot flashes or night sweats, trouble sleeping, mood changes or anxiety, brain fog and vaginal dryness. The menopausal transition most often begins between ages 45 and 55, though some women notice changes earlier. If symptoms are affecting your life, an online visit with a licensed provider is a good place to start.

Can perimenopause start at 38 or 39?

Yes, some women notice perimenopause symptoms in their late 30s, though it more commonly begins in the mid to late 40s. Other conditions, such as thyroid problems, can cause similar symptoms, so a licensed provider may suggest checking for them. Menopause before 40 is considered early and is worth discussing with a provider.

Do I have to wait until the hot flashes start before I can try HRT?

No, hot flashes are not required; hormone therapy may be considered for other bothersome symptoms, such as night sweats, sleep disruption and vaginal dryness, depending on your health history. The Menopause Society states that for healthy women under 60 or within 10 years of menopause, the benefits of hormone therapy for symptoms generally outweigh the risks. A licensed provider will review your symptoms and history in the online visit.

Can I take HRT if I'm still getting my period?

Yes, many women in perimenopause use hormone therapy while still having periods, though the type and schedule may differ from postmenopausal regimens. Standard HRT doses are not birth control, so some women in perimenopause still need contraception. A licensed provider can recommend options based on your cycle and goals.

Can HRT help with perimenopause anxiety and mood swings?

Hormone therapy may ease mood symptoms that come with perimenopause for some women, especially alongside hot flashes and poor sleep, but it is not a stand-alone treatment for anxiety disorders or depression. If you have significant anxiety, panic or low mood, tell your licensed provider, and if you ever have thoughts of harming yourself, call or text 988 right away. Some women do best with HRT combined with other mental health care.

Are joint pain, itchy skin and heart palpitations really perimenopause symptoms?

Many women report joint aches, dry or itchy skin, palpitations and headaches during perimenopause, and changing hormone levels may play a role. These symptoms can also have other causes, so new palpitations or chest pain should be checked promptly, in person if severe. Describe all your symptoms in your online visit.

What's the difference between perimenopause and menopause?

Menopause is the point 12 months after your last period, and perimenopause is the transition before it, when hormones fluctuate and periods become irregular. The menopausal transition most often begins between ages 45 and 55 and can last several years. Symptoms can continue after menopause too.

Ready to start?

A licensed provider reviews your online visit and decides whether Perimenopause Care is right for you.