Product image is illustrative. Your medication and packaging may look different.
No. 03 · Weight loss
Microdose GLP-1
Lower weekly dose, semaglutide or tirzepatide
Microdose GLP-1 means a lower weekly dose of compounded semaglutide or tirzepatide than a standard weight program uses, which a licensed provider may consider for a gentler start or for maintenance. There is no standard definition of microdosing and little research on very low doses, so no result is promised; microdose semaglutide is $170 a month and microdose tirzepatide is $235 a month.
A lower-dose GLP-1 option.
| Option | Monthly | Quarterly, 3 months | Start |
|---|---|---|---|
| Microdose semaglutide | $170 | $300about $100 a month | Start |
| Microdose tirzepatide | $235 | $485about $162 a month | Start |
Prices include the online visit, licensed provider review, medication and shipping. Quarterly plans ship three months at a time. Cancel or pause anytime. Available online in Detroit, Metro Detroit and across Michigan, and in other states where our providers are licensed.
Online visits for Detroit, Metro Detroit and Michigan. Questions first? Email support@hoolongevity.com or call (586) 321-3377.
Who it's for
- Women who want a gentler GLP-1 option and accept that low-dose research is limited
- Women maintaining after a standard GLP-1 program, at their provider's discretion
Not for
- A personal or family history of medullary thyroid carcinoma or MEN 2
- Pregnancy, trying to conceive or breastfeeding
- A history of pancreatitis, or type 1 diabetes, unless your provider approves
- Anyone under 18
Your licensed provider reviews your full history and decides what is appropriate.
How it works
Complete the online weight visit, including your height, weight, health history and medicines
A licensed provider reviews it and decides whether a GLP-1 is appropriate, and at what dose
Your medication ships from a licensed US pharmacy with supplies, cold where needed
Your care team adjusts the dose over time and answers questions by message
What's included
- Online visit and licensed provider review
- Compounded microdose semaglutide or tirzepatide and supplies
- Temperature-controlled shipping
- Messaging with your care team
Important safety information
- The most common side effects are nausea, vomiting, diarrhea, constipation and stomach pain, especially when the dose goes up. Eat smaller meals and stop eating when full.
- Not for anyone with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN 2). Tell your provider about a lump or swelling in your neck.
- Get help right away for severe stomach pain that does not go away (possible pancreatitis), pain in the upper right belly or yellow skin (possible gallbladder problems), or signs of dehydration.
- If you take insulin or a sulfonylurea, the risk of low blood sugar is higher. Do not use during pregnancy; stop before trying to conceive as your provider advises.
- Measure every dose exactly as labeled. The FDA has received reports of dosing errors with compounded GLP-1 medications, often from confusion about units and syringes.
- Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.
Prescription only. A licensed provider reviews your health history in an online visit and decides whether this program is appropriate for you. Tell your provider about every medication, supplement, allergy and condition, and whether you are pregnant, trying to conceive or breastfeeding. If you have a severe reaction, trouble breathing, chest pain or swelling of the face or throat, call 911.
Full details: safety information. Updated November 3, 2026.
Questions, answered
Straight answers about Microdose GLP-1.
What is a GLP-1 microdose?
A lower weekly dose of semaglutide or tirzepatide than standard weight programs use. There is no standard definition and little research on very low doses, so your provider decides whether it fits you.
How much does microdosing cost?
Microdose semaglutide is $170 a month or $300 a quarter. Microdose tirzepatide is $235 a month or $485 a quarter.
Is compounded semaglutide or tirzepatide FDA-approved?
No. Compounded GLP-1 medications are prepared by licensed US pharmacies for individual patients and are not FDA-approved. Brand-name versions are FDA-approved and are a separate option to discuss with your provider.
Sources
- Wilding et al., Once-Weekly Semaglutide in Adults with Overweight or Obesity, N Engl J Med (2021)
- Jastreboff et al., Tirzepatide Once Weekly for the Treatment of Obesity, N Engl J Med (2022)
- NIDDK, Prescription Medications to Treat Overweight and Obesity
- FDA, FDA's concerns with unapproved GLP-1 drugs used for weight loss
- FDA, Compounding and the FDA: Questions and Answers
Reviewed November 3, 2026.
Read more
Health GuideSemaglutide vs Tirzepatide: Which GLP-1 Is Right for You?
Both are once-weekly injections that lower appetite. Tirzepatide also acts on GIP, and in a 2025 head-to-head trial of the brand-name medicines it led to greater average weight loss than semaglutide. Side effects are similar, and a licensed provider helps you choose.
Weight LossGLP-1 Microdosing and Sublingual Drops: What to Know
Microdosing means a lower dose of semaglutide or tirzepatide than standard weight programs use, and sublingual drops are a needle-free form placed under the tongue. Both appeal to women who want a gentler option, but research on either is limited.
Ready to start?
A licensed provider reviews your online visit and decides whether Microdose GLP-1 is right for you.